Basic Information
VIS ID
TVIS44002916
Fusion event
HTLV-1-SLC45A3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
205639006/205669878 (Hg38)
End
205639006/205669878 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC45A3
miRNAs that regulate target gene
hsa-mir-138-5p ; hsa-mir-126-3p ; hsa-mir-126-5p ; hsa-mir-32-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-101-1/Upstream/221480; hsa-mir-1182/Downstream/804925;
Nearest TSS
ENST00000473358/Upstream/7210; ENST00000421166/Downstream/10581;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/6752, chr1-CpG: 99/Downstream/9969
Upstream sequence
GAAATCGGGGGCTGGTGAGGCACGAGGAATAATGACTCAGCTGAGGAAAGCGGGTGGGGTCACCCTGGGCCAACCTCCCGGACACACACCCCACCAAGGC
Downstream sequence
TGCCCTGCCCCAGGTCAGTGAGATGGCAGAGAAGGGGCAACCCCAGCACCTTGCTCCAAACTGAGCTCTCCAGGGTCCTCTAGGTTGGGGGCAGGGAGTG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate