Basic Information
VIS ID
TVIS44002918
Fusion event
HTLV-1-DMBT1P1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q26.13
Reference genome
GRCh37/hg19
Start
124520791/122761275 (Hg38)
End
124520791/122761275 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA10D ; FRA10F ; FRA10A ; FRA10B
Target gene
DMBT1P1
Nearest miRNA
hsa-mir-107/Upstream/344208; hsa-mir-202/Downstream/2271508;
Nearest TSS
ENST00000439456/Upstream/61453; ENST00000368894/Downstream/76823;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/117827, chr10-CpG: 41/Downstream/57335
Upstream sequence
AGAGTTCTAAACGTACTGGATTTTCCATCCCATTATGCTCTAACTAGCGATAGATGAATGTGGTAGAGAAGGGAGAGTGGATGATCCTCCCTACCTGAAT
Downstream sequence
CTGCCTCTTGGGGAGCCAACCAAAACACTGACTGGACACATTTGAGCCCAGTCATTCTCTTTGGGCTTGTTGTCAGAAGTTTTCCCTTCTGTGTGTAGCT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate