Basic Information
VIS ID
TVIS44002920
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
46084854/48007488 (Hg38)
End
46084854/48007488 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/1034388; hsa-mir-10226/Downstream/25394;
Nearest TSS
ENST00000595228/Upstream/11292; ENST00000583060/Downstream/21072;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/36031, chr17-CpG: 30/Downstream/4782
Nearby gene
COPZ2(-18679) ;
Upstream sequence
cagacgcagatcacagcagttttatttgtttgtttgtttagagtttcactctgtctcccaggctagagtgcagtgtcacaatctcggctcactgcaacct
Downstream sequence
ccgcctcccggattcaagcaatgcctgtgcctcagcctcccagtagctgggattacaccaccacgccaagctaattttagtatttttagtagagacaagg
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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