Basic Information
VIS ID
TVIS44002922
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.32
Reference genome
GRCh37/hg19
Start
44204405/44162913 (Hg38)
End
44204405/44162913 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12127/Upstream/48603; hsa-let-7g/Downstream/698975;
Nearest TSS
ENST00000440867/Upstream/45614; ENST00000309765/Downstream/78973;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/140568, chr3-CpG: 48/Downstream/78834
Nearby gene
MIR138-1(+48603) ;
Nearest cancer related gene
MIR138-1(TSG, +48603) ;
Upstream sequence
TCAATCACCTCCAACTCATTCAATCCAACTCCAATACTCTCACTGCAGTTGCTATGTTCAttcaggcatcacatgcaaatggccagaggcagaaggggat
Downstream sequence
ctgcctcttttttgcaatttaaaaaatgaagatgcctgtcaagaaagaccccagctgcctattcctcacactcgctatattatatcatctacccttgtct
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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