Basic Information
VIS ID
TVIS44002923
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q24
Reference genome
GRCh37/hg19
Start
147879187/148161400 (Hg38)
End
147879187/148161400 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/13723494; hsa-mir-1224/Downstream/3404476;
Nearest TSS
ENST00000440867/Upstream/489; ENST00000470219/Downstream/30319;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/736796, chr3-CpG: 56/Downstream/536255
Nearby gene
AGTR1(+536471) ;
Nearest cancer related gene
AGTR1(TSG, +536471) ;
Upstream sequence
ATAAAAGTAGTGAAAATATAATAcagttaacccttgaacaatactacgtgggtccacttttattagagttctcttcaataaaagttaaccccgagtgtgt
Downstream sequence
ctgcctcttttgttcccctttcatctcctcttcatcttctgcctctgccacacagagacagcaagaccacccgaagggttggtcctcctccttctcagcc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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