Basic Information
VIS ID
TVIS44002934
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
GRCh37/hg19
Start
2450886/2429656 (Hg38)
End
2450886/2429656 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-210/Upstream/256518; hsa-let-7a-2/Downstream/1426406;
Nearest TSS
ENST00000527297/Upstream/6611; ENST00000380776/Downstream/15028;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/8484, chr11-CpG: 37/Downstream/14285
Nearby gene
TRPM5(-6611) ;
Upstream sequence
atgatcctggtggtggCCATGGTggtgtttttgataacgtgataatgttggagatggtggtgattgtggtggtgataatggtggtcatggtgatggtgat
Downstream sequence
atcagtgtgggtgatgtagtggtggggatggttcagatgttggtgatggtggtggtgatggcagtgatagttaggatgatggtgatgatgatgatggcat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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