Basic Information
VIS ID
TVIS44002947
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
81201323/80289088 (Hg38)
End
81201323/80289088 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12123/Upstream/47615; hsa-mir-10400/Downstream/10916397;
Nearest TSS
ENST00000518652/Upstream/22934; ENST00000379091/Downstream/196531;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/23132, chr8-CpG: 188/Downstream/196754
Nearby gene
MIR5708(No orient, 47615)
Upstream sequence
AAAAGGAAAACTGAGTGAGTACAGGAAAAAGGACACATATATCTTTATATATCTCCTATTGCAGTCAATTTTGTGGTAGGTGTTACTTCAATGGCTGCAA
Downstream sequence
GTCAATGACCATGAGGCCCACTTGTTAAAAATATGAAACAAAGCCAGCTTTGTtggctcacacttgtgatcccaacactttgggaagccgaggcaggaag
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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