Basic Information
VIS ID
TVIS44002965
Fusion event
HTLV-1-CALD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q33
Reference genome
GRCh37/hg19
Start
134615369/134930618 (Hg38)
End
134615369/134930618 (Hg38)
Orient
+
Location type
Intronic
Target gene
CALD1
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-34a-5p ; hsa-mir-21-5p ; hsa-mir-149-5p ; hsa-mir-15a-5p
Nearest miRNA
hsa-mir-10525/Upstream/1639630; hsa-mir-10399/Downstream/276376;
Nearest TSS
ENST00000635602/Upstream/10052; ENST00000478075/Downstream/10523;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/471307, chr7-CpG: 63/Downstream/55750
Upstream sequence
GCTGTATTAGAAGGTTTCAGAAAGCAGTCTTGAAAATGTTGGCCGGTAGCACAATATTGTTTACCCTTTCCCTCAATAAGTAGCTTCTAATTGGGGAGTA
Downstream sequence
GGTATAGCAAAGGGGAAATAGGTATAATTTCTAGGGTTCACTAATTGACTTTGACTCCCAatttgacctttcactaactgtatttcttcagttaaatgga
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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