VISDB Viral Integration Site DataBase

VIS ID

TVIS44003001

Fusion event

HTLV-1-ARMH3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q24.32

Reference genome

Start

End

103675288/101915531 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA10D ; FRA10A ; FRA10B

Target gene

miRNAs that regulate target gene

hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-555 ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-6510-5p ; hsa-mir-6732-5p ; hsa-mir-3936 ; hsa-mir-4520-3p ; hsa-mir-6721-5p ; hsa-mir-6860 ; hsa-mir-5189-5p ; hsa-mir-612 ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-4638-3p ; hsa-mir-922 ; hsa-mir-10b-3p ; hsa-mir-6501-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-7154-5p ; hsa-mir-6748-5p ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-3165 ; hsa-mir-4483 ; hsa-mir-1293 ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-4680-5p ; hsa-mir-8060 ; hsa-mir-383-3p ; hsa-mir-4761-5p ; hsa-mir-1273e ; hsa-mir-1827 ; hsa-mir-3929 ; hsa-mir-4419b ; hsa-mir-4478 ; hsa-mir-4649-3p ; hsa-mir-4722-5p ; hsa-mir-4768-3p ; hsa-mir-485-5p ; hsa-mir-658 ; hsa-mir-665 ; hsa-mir-6808-5p ; hsa-mir-6840-3p ; hsa-mir-6884-5p ; hsa-mir-6893-5p ; hsa-mir-7160-5p ; hsa-mir-7846-3p ; hsa-mir-940

Nearest miRNA

hsa-mir-107/Upstream/314034; hsa-mir-1307/Downstream/520981;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/71862, chr10-CpG: 72/Downstream/140214

Upstream sequence

TTCAGTATTATTGCTGCAAGTAATGCAATACTACTATCACCATGTATGCCCCCTTCCTGAGCAACTGAATAGAGATAGTTTGGCATTTGGGAAGGCATTT

Downstream sequence

CAAGTTGACCATGAGAAGCAAACACTGTATACACACAGTTCAGATCACTGGAGACGTGGCAGAAAGGGAGGAAGGAGGCACAGTAGCTGTCTGCAATAGT