Basic Information
VIS ID
TVIS44003010
Fusion event
HTLV-1-LINC01570 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
5655617/5605616 (Hg38)
End
5655617/5605616 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC01570
Nearest miRNA
hsa-mir-1225/Upstream/934226; hsa-mir-11401/Downstream/26851;
Nearest TSS
ENST00000527434/Upstream/365801; ENST00000548749/Downstream/5677;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/365231, chr16-CpG: 127/Downstream/413297
Upstream sequence
CTTTGGTATAGGAGGGCagagtggtgccattgattagtaatgtctgccatgggtctgggaggggagagtggtgccacTGATGAGTAATGTCTGCCTTGGG
Downstream sequence
TCTAGGAGGGGAGAGTGGTGCCATTGATGAGTAAGTCTGCCTTGAGTCTAGGAGGGGAGAGTGTTGTCCTTGATGAGTAATGTCTACCTCAGGTCTAGGA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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