Basic Information
VIS ID
TVIS44003012
Fusion event
HTLV-1-GATAD2A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
End
19597714/19486905 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-10a-5p ; hsa-mir-103a-3p ; hsa-mir-98-5p ; hsa-mir-16-5p ; hsa-mir-615-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-1322 ; hsa-mir-5187-5p ; hsa-mir-1276 ; hsa-mir-4640-5p ; hsa-mir-4726-5p ; hsa-mir-548c-3p ; hsa-mir-4311 ; hsa-mir-211-3p ; hsa-mir-4648 ; hsa-mir-92b-5p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-4745-5p ; hsa-mir-4328 ; hsa-mir-4481 ; hsa-mir-4681 ; hsa-mir-583 ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-92a-2-5p ; hsa-mir-5010-5p ; hsa-mir-7111-5p ; hsa-mir-4525 ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6845-5p ; hsa-mir-6762-5p ; hsa-mir-6825-5p ; hsa-mir-7106-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4779 ; hsa-mir-4261 ; hsa-mir-3529-3p ; hsa-mir-1305 ; hsa-mir-1237-3p ; hsa-mir-1248 ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-18a-5p ; hsa-mir-18b-5p ; hsa-mir-1908-5p ; hsa-mir-195-5p ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-3196 ; hsa-mir-3612 ; hsa-mir-3908 ; hsa-mir-3925-3p ; hsa-mir-424-5p ; hsa-mir-4305 ; hsa-mir-4443 ; hsa-mir-4466 ; hsa-mir-4706 ; hsa-mir-4735-3p ; hsa-mir-4749-5p ; hsa-mir-4777-5p ; hsa-mir-4787-5p ; hsa-mir-4802-5p ; hsa-mir-497-5p ; hsa-mir-518d-5p ; hsa-mir-518e-5p ; hsa-mir-518f-5p ; hsa-mir-519a-5p ; hsa-mir-519b-5p ; hsa-mir-519c-5p ; hsa-mir-520c-5p ; hsa-mir-522-5p ; hsa-mir-523-5p ; hsa-mir-526a ; hsa-mir-589-3p ; hsa-mir-6502-3p ; hsa-mir-650 ; hsa-mir-663a ; hsa-mir-6730-5p ; hsa-mir-6753-5p ; hsa-mir-675-5p ; hsa-mir-6787-5p ; hsa-mir-6816-5p ; hsa-mir-6827-5p ; hsa-mir-6838-5p ; hsa-mir-6868-3p ; hsa-mir-744-5p ; hsa-mir-766-3p
Nearest miRNA
hsa-mir-10395/Upstream/51747; hsa-let-7e/Downstream/912367;
Upstream sequence
TCACCTCACCAGGCAGCCCTGAGAGGCTGCGGGACAGGGATTCCTCTGCCCTGCCATGCAGGAGCCATGGAGAGGGAAGTGTCACTTGCAAGAGGCAGAA
Downstream sequence
TCAAGTGAGACCCAGGTGTCTTCTAGCTCACTGGGTGAGGGCTCTCTCCACAGCCTGACTTGCCGGCAGTCGTTTGAAGTCCAAGGCTGGGCAAGGGTGG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate