Basic Information
VIS ID
TVIS44003017
Fusion event
HTLV-1-RIMS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q13
Reference genome
GRCh37/hg19
Start
72616838/71907135 (Hg38)
End
72616838/71907135 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6D
Target gene
RIMS1
Nearest miRNA
hsa-mir-10398/Upstream/503514; hsa-mir-10524/Downstream/1060552;
Nearest TSS
ENST00000381078/Upstream/20111; ENST00000524197/Downstream/275617;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/20070, chr6-CpG: 100/Downstream/275199
Upstream sequence
CTCTTATTCATTGTAGTGATTTTAGCACAATGCAGTTACCTGAGCTTTGGGAATACACAGAAGTTGGGTGCTTTCTTTTGAACTAGGGTAGTAAACCTTC
Downstream sequence
TTTTAGCAGCACTTTGGAATAGATTTACCCTGCATTATGCTTACAGATTTAATTCCTCACATTTGTTGTTTTACTAAGGAAGCATTTTGGCTTACCCCTC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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