Basic Information
VIS ID
TVIS44003026
Fusion event
HTLV-1-NAALADL2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q26.31
Reference genome
GRCh37/hg19
Start
174159134/174441344 (Hg38)
End
174159134/174441344 (Hg38)
Orient
-
Location type
Intronic
Target gene
NAALADL2
Nearest miRNA
hsa-let-7g/Upstream/3334585; hsa-mir-1224/Downstream/928196;
Nearest TSS
ENST00000440867/Upstream/357; ENST00000485853/Downstream/417936;
Nearest CpG islands
chr3-CpG: 107/Target, None/Upstream, None/Downstream
Nearby gene
NLGN1(+157995) ;
Upstream sequence
CTGAGCGACTCCGCGGGGTGGCGCGCGGGGCACCTGGCTCTGGCAGTCCGCGAGGCGCGCTGGCCAAAGGAGCTCCCAACCCGCTCCAAGGCCCCCGCCC
Downstream sequence
ACCTCCCGAAGCCGCTTGTCTTAGGAGAGGAGCGTAGCAGCTCCGAGTCCCCGCTTCTGACACGTTCACACACGTATGCAGTGCACGCCGGCCAGGCAGC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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