Basic Information
VIS ID
TVIS44003030
Fusion event
HTLV-1-SYT16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
62356171/61889453 (Hg38)
End
62356171/61889453 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA14B
Target gene
SYT16
Nearest miRNA
hsa-mir-208a/Upstream/1240742; hsa-mir-1185-1/Downstream/2205571;
Nearest TSS
ENST00000550708/Upstream/24573; ENST00000430451/Downstream/106370;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/24530, chr14-CpG: 25/Downstream/167404
Nearby gene
SNAPC1(+93025) ;
Upstream sequence
ccctaaactgactgctatagtttaggtgtttgtccccctaaacctcatgttgaaatctgatttcaatgttggaggtggggctgtaatgggagacgtttgg
Downstream sequence
gtcaagggaatggatccctcatgactccattaatgccctctctggagggcagatgagtgagttctttctctattagttcctgcaaaagctgtttgttaaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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