Basic Information
VIS ID
TVIS44003048
Fusion event
HTLV-1-RORA-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
60772881/60480682 (Hg38)
End
60772881/60480682 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA15A
Target gene
RORA-AS1
Nearest miRNA
hsa-mir-10393/Upstream/1309420; hsa-mir-11181/Downstream/1823976;
Nearest TSS
ENST00000557528/Upstream/1462; ENST00000560280/Downstream/29726;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/1323, chr15-CpG: 200/Downstream/110417
Upstream sequence
aacttctgccacctgggttcaagcgattctcctgcgtcagtctccctagtagctgggactacaagtgcatgccaccacacttggctaatttttgtatttt
Downstream sequence
ttttttagtagagatggggtttgccagggtgatctttaactcttgacctcaagtgatctgcccaccttggcctccctaagtgctgggattacaggtgtga
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate