Basic Information
VIS ID
TVIS44003066
Fusion event
HTLV-1-MIR3134 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q32
Reference genome
GRCh37/hg19
Start
115097438/112335158 (Hg38)
End
115097438/112335158 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA9E
Target gene
MIR3134
Nearest miRNA
hsa-let-7a-1/Upstream/402989; hsa-mir-12126/Downstream/1874276;
Nearest TSS
ENST00000422679/Upstream/1491; ENST00000480881/Downstream/44779;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/985, chr9-CpG: 70/Downstream/44416
Upstream sequence
TGTATTTGGGATATATTCTGTTGATGAAATTTCCTTAACCCTTTTTTTAGCTACACAAGTAATATCAGCATAAATGCTCATTTTGGAAAATTCAAGCACT
Downstream sequence
ATAAAATATTGAAAAGTTATCATTAATATTTTTCTTCCCAAACCACCCCCTGCCCATGACTACCACTGTAACAATTCTGCGTGCATCCTTCTGGACCTTA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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