Basic Information
VIS ID
TVIS44003082
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
54387067/53812932 (Hg38)
End
54387067/53812932 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-15a/Upstream/1002792; hsa-mir-1267/Downstream/499040;
Nearest TSS
ENST00000623511/Upstream/467721; ENST00000569422/Downstream/2487;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/610722, chr13-CpG: 25/Downstream/3327905
Nearby gene
LINC00558(No orient, 2487)
Upstream sequence
ATTCATTCTAGCCCCAGCAGAAGTATGAATAGGACAGTGACTGCCTTCCCAGTTAATTTCATCCTGCTGCTTCTTTTCAGGAGAGGGAGGGTAGTTAATT
Downstream sequence
TTCCCTTTTCAGTTCTTAACATTTGATAGTAACTGACTTAAAACGATAATTCATTTTTTTGAGAGTCTTCTTTCCCTCCTACAGTGTAAAAAGAGATTGT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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