Basic Information
VIS ID
TVIS44003084
Fusion event
HTLV-1-IGH integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.33
Reference genome
GRCh37/hg19
Start
106158146/105691809 (Hg38)
End
106158146/105691809 (Hg38)
Orient
-
Location type
Intronic
Target gene
IGH
Nearest miRNA
hsa-mir-1185-1/Upstream/51577; hsa-mir-4507/Downstream/165704;
Nearest TSS
ENST00000550708/Upstream/21966; ENST00000414005/Downstream/16856;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/4782, chr14-CpG: 18/Downstream/5701
Nearby gene
ELK2AP(-19002) ;
Upstream sequence
GCCTCGGGGAAACCCACAGATACACACGGGACCCCGAACATCGGGCTGGGGAGGTTGGGGTGGGTAACAGCATGCCAGAGGCAGGAGCAGGAGGTCCAGG
Downstream sequence
ACCCTGCGCACTGCGACCCCAGCCCTGGGGGCTGAAGCCCAGGACAGCCTCAGGTCTCCCAGGAGGGACTGGACAGTGGGGGATGGTCAGAGAACAGGAC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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