Basic Information
VIS ID
TVIS44003104
Fusion event
HTLV-1-LOC101927400 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
114083016/113325439 (Hg38)
End
114083016/113325439 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2B
Target gene
LOC101927400
Nearest miRNA
hsa-mir-1285-2/Upstream/1554305; hsa-mir-10b/Downstream/257520;
Nearest TSS
ENST00000437798/Upstream/46489; ENST00000453673/Downstream/80957;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/241, chr2-CpG: 39/Downstream/112149
Nearby gene
PAX8(-46518) ;
Upstream sequence
CTGCAGACTCCAGGGAACTTCCTCCCCTCAAAGACGAACTTCCAGCCCTGGAGCATGTTTCTTCCTTTCCTGGGATGTGGCGCTGAAAAGGGCAGAAACC
Downstream sequence
TCTAGTAAGGCACAAGCAACAGATTGGGGGTGGAGCAGCAGGTCTCTTTGGAGGTGGCCTGGAAGAAACCGGACAGAGAGGATGGGAAGGGGAGAAACAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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