Basic Information
VIS ID
TVIS44003115
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
9079514/9079516 (Hg38)
End
9079514/9079516 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3976/Upstream/2705091; hsa-mir-1-2/Downstream/1680068;
Nearest TSS
ENST00000575820/Upstream/249593; ENST00000497577/Downstream/23114;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/293870, chr18-CpG: 58/Downstream/22902
Nearby gene
NDUFV2(+23114) ;
Upstream sequence
attataggtgtgagccaccatgtccggccCtttctttctttctacaggcagggtctcaccctgtcacccaggcatagtggtgcctcatggttcactgcag
Downstream sequence
ccttgacctcctaggctcaagtgatcctcctacctcagcatcccaagtagctgggactactggcacatgccaccacgcccagctaatttttttatttttt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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