Basic Information
VIS ID
TVIS44003121
Fusion event
HTLV-1-ERI3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.1
Reference genome
GRCh37/hg19
Start
44735143/44269471 (Hg38)
End
44735143/44269471 (Hg38)
Orient
-
Location type
Intronic
Target gene
ERI3
miRNAs that regulate target gene
hsa-mir-455-3p
Nearest miRNA
hsa-mir-12136/Upstream/430788; hsa-mir-101-1/Downstream/276022;
Nearest TSS
ENST00000473358/Upstream/12550; ENST00000487332/Downstream/50279;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/55678, chr1-CpG: 45/Downstream/85514
Upstream sequence
tgccCTCCAAGGACAAGGGCCTCATCTGCCCACCTCTAGTGCCTAGAGTCAGACCACAAATCCCATACTGGCACATTCACCCACATTCCCATTTGTGGGC
Downstream sequence
CCGTGCACACATAAGAATATACACAGACATACTCAAGCCTGCACAGACCTCCCCAATTGGGTGAATGCACTTCTTTAAACACATACAGACATGCATATAC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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