Basic Information
VIS ID
TVIS44003143
Fusion event
HTLV-1-TRAF3IP2-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
GRCh37/hg19
Start
111892770/111571567 (Hg38)
End
111892770/111571567 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA6F
Target gene
TRAF3IP2-AS1
Nearest miRNA
hsa-mir-10398/Upstream/4787347; hsa-mir-1202/Downstream/7497480;
Nearest TSS
ENST00000381078/Upstream/4207; ENST00000607066/Downstream/2419;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/87261, chr6-CpG: 116/Downstream/301065
Upstream sequence
tcccaaagtgctaggattacaggcatgagccaccacgcctggcTGCTATAGTGCTTTCTTATACCAGAAATGAGAAAGGGAAATATTAGTCTCTATATAA
Downstream sequence
TTATGGAGTTGGATTGTATAAGTTGTATGCATTTTTTAAAAAAGAACTTTCATTTTCATTTTTTAGAAAATTGTCTTggccgagtgcagtgactcacacc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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