Basic Information
VIS ID
TVIS44003144
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
131823235/131502095 (Hg38)
End
131823235/131502095 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/5017382; hsa-mir-1202/Downstream/290077;
Nearest TSS
ENST00000381078/Upstream/251665; ENST00000484820/Downstream/71049;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/366078, chr6-CpG: 42/Downstream/125852
Nearby gene
ARG1(+71109) ;
Nearest cancer related gene
ARG1(TSG, +71109) ;
Upstream sequence
ttttttcatagcagcgagagaatggactaatacaGGAAGCTATGTTTTTTGTCTTTCCCACTGGGTATAAACAAGCAAGTTTATATGGTTCTACTTCTAT
Downstream sequence
GTCTTACAAATATGAGTGTAACCAACCTTGGGATGAAACTGACCCTGTAGATGAACCAggagagacctgggtccccaatgacatcattgacttgcaaaat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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