Basic Information
VIS ID
TVIS44003155
Fusion event
HTLV-1-COL15A1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
101813278/99050996 (Hg38)
End
101813278/99050996 (Hg38)
Orient
-
Location type
Intronic
Target gene
COL15A1
miRNAs that regulate target gene
hsa-mir-29c-3p ; hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-29b-3p
Nearest miRNA
hsa-let-7a-1/Upstream/821779; hsa-mir-12126/Downstream/7549932;
Nearest TSS
ENST00000422679/Upstream/12323; ENST00000548365/Downstream/53042;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/65195, chr9-CpG: 142/Downstream/53716
Upstream sequence
GGCATCCAAGTCTGCAGCTCAGGGCCTGGGAACTCTGGCCTAGAGGGCAGGACCCACCTATGTCAGGTGACTAACGGGCTCCAGGCTCTACATGGAGACA
Downstream sequence
ACAGCAACCCAGTATGTGTTTATATCCATGGCCTGAAGagaaacataaaatctcagtgctggagtgaccttcctgggcagtcgctgcatcccacctgctt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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