Basic Information
VIS ID
TVIS44003162
Fusion event
HTLV-1-LOC105369876 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
85817052/85423274 (Hg38)
End
85817052/85423274 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12B
Target gene
LOC105369876
Nearest miRNA
hsa-let-7i/Upstream/4264813; hsa-mir-1178/Downstream/1321794;
Nearest TSS
ENST00000382841/Upstream/105214; ENST00000551529/Downstream/413296;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/142352, chr12-CpG: 52/Downstream/2612054
Nearby gene
ALX1(+121491) ;
Upstream sequence
TAGCCCTCATTCTTATGACCCCAAATTAGGTAGTTCTTCATGTCTTAGAAAGATGAGAGAAGTAAATAATATAAAAAGACAAAATACACTTTAAAAAATG
Downstream sequence
TAAAGCATCTATAAACCTCATGGTGGTTACAAGGAAATACAGAGACATAAGGAAAAAATACAGATGACACCATGGCTAATATCCTTCTTCACAATTCAGG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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