Basic Information
VIS ID
TVIS44003171
Fusion event
HTLV-1-chr19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.12
Reference genome
GRCh37/hg19
Start
14491684/14380872 (Hg38)
End
14491684/14380872 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA19B
Nearest miRNA
hsa-mir-10395/Upstream/307393; hsa-let-7e/Downstream/148671;
Nearest TSS
ENST00000633603/Upstream/371; ENST00000587606/Downstream/284;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/47100, chr19-CpG: 50/Downstream/25042
Nearby gene
ADGRE5(No orient, 272)
Upstream sequence
ctgggactacagatgtctgccaccagcctggattatttatttatttattttgtagaaacaagagtttcgccatgttgcccaggctggtgtcaaactcctg
Downstream sequence
agctcaagcgatcctcctgcctcggcctcccagagtgctgagatcacaggtgcgagcctctgcacccgaccTGTTTCCTCATCTGGAAAATGGCAGGGAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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