Basic Information
VIS ID
TVIS44003189
Fusion event
HTLV-1-RXYLT1-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
64211061/63817281 (Hg38)
End
64211061/63817281 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
RXYLT1-AS1
Nearest miRNA
hsa-let-7i/Upstream/1213512; hsa-mir-10527/Downstream/6382;
Nearest TSS
ENST00000382841/Upstream/12330; ENST00000542381/Downstream/4875;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/36823, chr12-CpG: 45/Downstream/4438
Upstream sequence
AAATGAAAGATAATCACTCTTCTCTGATAGGTTAACCAATTCTTctaaaattagtggtctgataagaagcaggagatttacatagtctcaaagtatttcc
Downstream sequence
ttgcaatatacttaactagttataaaggaaaaaacatacaagtttacagttgagaaagcaccaacttaaccaactgatcaatacattatcagtaatggga
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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