Basic Information
VIS ID
TVIS44003191
Fusion event
HTLV-1-ARLNC1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
80926135/80892238 (Hg38)
End
80926135/80892238 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA16D
Target gene
ARLNC1
Nearest miRNA
hsa-mir-1225/Upstream/4023219; hsa-mir-11401/Downstream/492780;
Nearest TSS
ENST00000527434/Upstream/21718; ENST00000568445/Downstream/322;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/87275, chr16-CpG: 52/Downstream/39817
Upstream sequence
gttaactgTTTGATTAATAAGAAACTAGCTCCAGATGTATCTGTGTCTTCAGAGACCGTCCTTTACCTCTAAACcagtgactctcaaagtagaggactca
Downstream sequence
accagcagcagcagcagccgcacctgggaacttcttagaaacgcaaattctcagggctcaccccagccctgctgaatcagaaactataggggtagggtcc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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