Basic Information
VIS ID
TVIS44003214
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
32275392/33687586 (Hg38)
End
32275392/33687586 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/1449739; hsa-mir-1-1/Downstream/361533;
Nearest TSS
ENST00000382410/Upstream/1182; ENST00000342427/Downstream/32714;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/887, chr20-CpG: 36/Downstream/32425
Nearby gene
E2F1(-1182) ;
Nearest cancer related gene
E2F1(OG, -1182) ;
Upstream sequence
TAGGGAGCCCTCCCAAGGATTTACTCACTTCCTCTATTGCCCACTGCTGCCTCTGCTCCAATGCTGACCACACACACTCCTTTTCTCCATCTGCCTCCCC
Downstream sequence
TGCCAATCTAGGAGCTCAGTAGCGACTCCTCCCAACACTGGTCTGGCCCAGAGCAGGCGCTGAGAAAGGTTATGAAAGAAACAGAGGCTAAGCCAGAGGC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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