Basic Information
VIS ID
TVIS44003226
Fusion event
HTLV-1-MIR548AE2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
48281585/48247674 (Hg38)
End
48281585/48247674 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
MIR548AE2
Nearest miRNA
hsa-mir-1225/Upstream/14084001; hsa-mir-11401/Downstream/2044942;
Nearest TSS
ENST00000527434/Upstream/106; ENST00000570174/Downstream/15102;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/2930, chr16-CpG: 30/Downstream/118145
Upstream sequence
AGCTTTGGACTTGTCCTGCAGTATAGAACTTGGCTGGCATGCTGACCCAGGGCACCCTGCATTTTTCTGCTTAGTAGAACTGCATTTTTAGTGCTTCCTG
Downstream sequence
AGTGACCCATTGTTTTCTTAGTGAAAAGGGGTCATAATTTAGTACTACCTGTACAATATCCTTTCAAGCATTTCAAGATGGTCATCCAGCTTTCTTCCAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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