Basic Information
VIS ID
TVIS44003236
Fusion event
HTLV-1-PIP5K1B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
71446597/68831681 (Hg38)
End
71446597/68831681 (Hg38)
Orient
-
Location type
Intronic
Target gene
PIP5K1B
Nearest miRNA
hsa-mir-101-2/Upstream/27597846; hsa-let-7a-1/Downstream/1978294;
Nearest TSS
ENST00000422679/Upstream/51647; ENST00000396366/Downstream/11594;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/51105, chr9-CpG: 41/Downstream/181810
Upstream sequence
AAGACATTAAAACAGTGATTCTCAATTATCTGCAATAGTAGCAGGGGTCAGTAAGATAAACTCAGACAGCTTTGGAATGGGAACAAATTAATAGAATTTA
Downstream sequence
ACtttttttttttgacggagttttgctcttgttgcccaggctggagtgcagtggtgtgatctcagctcactgcaacctccgctgcccgggttcaagccac
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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