Basic Information
VIS ID
TVIS44003254
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
27559840/26187521 (Hg38)
End
27559840/26187521 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/613477; hsa-mir-3197/Downstream/766440;
Nearest TSS
ENST00000624081/Upstream/16393; ENST00000452460/Downstream/163113;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/16631, chr21-CpG: 61/Downstream/385170
Nearby gene
APP(-16394) ;
Upstream sequence
tacagtgtttacaactgaaagggatgaagtagtcatttaggccaagtctttaatttgatgaggacttactggagagccagataaatgaagtcccttgcat
Downstream sequence
atggtcatatgaatatttattggcaaagcttggcctttgtcctcctgacttccagATCTCATTTCATCTTGTGGTGCTTCCAGCATCTGGCCACCTTGCT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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