Basic Information
VIS ID
TVIS44003258
Fusion event
HTLV-1-PRRT3-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p25.3
Reference genome
GRCh37/hg19
Start
9989888/9948204 (Hg38)
End
9989888/9948204 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
PRRT3-AS1
Nearest miRNA
hsa-mir-4790/Upstream/4697949; hsa-let-7g/Downstream/332147;
Nearest TSS
ENST00000440867/Upstream/800; ENST00000602436/Downstream/4170;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/269, chr3-CpG: 44/Downstream/3842
Upstream sequence
gcaaaatggagataacagcacctgcctcattgcgttgtgaagaagatgaaatgtttagcccggtgcccaacacccagtaagtgctaaatggatgtcagct
Downstream sequence
atcattTTCATTAATGCTACTATCAGGGAGGTAGTACCCcagcagttcgacacatgggctgcatattagaatcttctggagaCCAAGGAATAAGAATTTC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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