Basic Information
VIS ID
TVIS44003280
Fusion event
HTLV-1-MINAR1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
79737138/79444796 (Hg38)
End
79737138/79444796 (Hg38)
Orient
-
Location type
Intronic
Target gene
MINAR1
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-10393/Upstream/234925; hsa-mir-11181/Downstream/1136307;
Nearest TSS
ENST00000557528/Upstream/12280; ENST00000559272/Downstream/11300;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/11495, chr15-CpG: 89/Downstream/451868
Upstream sequence
acctgtatgtttaaatttccgtgtgttcaggtgatatctttgggtatacatttgttaattttattaccttattgtaaaaaaaaaaatcactgcaggatat
Downstream sequence
aaattcatttttttaaaaatttgtatcataatatgtggccagcattacttgaaaagaatgtgtattcttgggtccaggttctctatatgtatagatcaag
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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