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TVIS44003286
Basic Information
VIS ID
TVIS44003286
Fusion event
HTLV-1-CLASP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
122373627/121616051 (Hg38)
End
122373627/121616051 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
CLASP1
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-4467
;
hsa-mir-6809-5p
;
hsa-mir-8072
;
hsa-mir-3960
;
hsa-mir-6722-3p
;
hsa-mir-1909-3p
;
hsa-mir-6836-5p
;
hsa-mir-6132
;
hsa-mir-4708-3p
;
hsa-mir-6087
;
hsa-mir-1205
;
hsa-mir-4441
;
hsa-mir-6754-5p
;
hsa-mir-4270
;
hsa-mir-4756-5p
;
hsa-mir-4739
;
hsa-mir-1321
;
hsa-mir-6751-5p
;
hsa-mir-6803-5p
;
hsa-mir-7110-5p
;
hsa-mir-6842-5p
;
hsa-mir-6752-5p
;
hsa-mir-6835-5p
;
hsa-mir-637
;
hsa-mir-3613-3p
;
hsa-mir-6852-5p
;
hsa-mir-7851-3p
;
hsa-mir-490-3p
;
hsa-mir-548as-3p
;
hsa-mir-548z
;
hsa-mir-548h-3p
;
hsa-mir-548d-3p
;
hsa-mir-548bb-3p
;
hsa-mir-548ac
;
hsa-mir-5003-5p
;
hsa-mir-8485
;
hsa-mir-3591-3p
;
hsa-mir-21-3p
;
hsa-mir-383-3p
;
hsa-mir-3065-3p
;
hsa-mir-6871-3p
;
hsa-mir-3620-3p
;
hsa-mir-504-5p
;
hsa-mir-4693-5p
;
hsa-mir-3119
;
hsa-mir-892c-3p
;
hsa-mir-4676-3p
;
hsa-mir-452-5p
;
hsa-mir-1283
;
hsa-mir-4320
;
hsa-mir-4456
;
hsa-mir-4654
;
hsa-mir-4766-3p
;
hsa-mir-4769-5p
;
hsa-mir-5089-5p
;
hsa-mir-541-3p
;
hsa-mir-548p
;
hsa-mir-6507-3p
;
hsa-mir-654-5p
;
hsa-mir-6769a-5p
;
hsa-mir-6769b-5p
;
hsa-mir-6838-3p
;
hsa-mir-92a-2-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/7894683; hsa-mir-10b/Downstream/5807486;
Nearest TSS
ENST00000437798/Upstream/9991;
ENST00000414554/Downstream/33387;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/85295
,
chr2-CpG: 104/Downstream/32771
Upstream sequence
GTTCAAAGCATGGGCATTTACTAACTGAAACATGAAAATGTTTCAGCTACAGCATGTGGGGCGTAAGAAGGAGAAAATTAAGAAACACGAAGTCAAATCA
Downstream sequence
TAAATAAGGAGTTCAAGAAGCCTTAATAAAATAATATTCCATACCAGAGTATCAAGAAGGAATTAAATTACCAGCACCAGTTAATCAATAACCACATTAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Sample Information
×
Sample name
ATL14-CR3
Sample type
Nontumor
Age
35
Gender
Female
CpG Island Information
×
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