Basic Information
VIS ID
TVIS44003293
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
128148623/128508569 (Hg38)
End
128148623/128508569 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10525/Upstream/300626; hsa-mir-10399/Downstream/1261814;
Nearest TSS
ENST00000635602/Upstream/14726; ENST00000605836/Downstream/22500;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/31311, chr7-CpG: 189/Downstream/21951
Nearby gene
METTL2B(+5645) ;
Upstream sequence
tcaaaaaaaaaagagagagaaaGGGaagaaggaaagaaaaaaaaaaagaaggaaagGAGGGAGGGAGGAACATTTATCAGCAGTGGCACACTTGAGAAAC
Downstream sequence
CCTCCAAGGGTGAGCAGAATGGCGAGGGCCCTGAAGAGCCCTGCTACTGACAAGCCCCTGTCACCCTCTTCAGCCTTGCTTCTGATTACCCCTCAATTTT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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