Basic Information
VIS ID
TVIS44003301
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
99305189/98839633 (Hg38)
End
99305189/98839633 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1M
Nearest miRNA
hsa-mir-101-1/Upstream/793462; hsa-mir-11399/Downstream/1441608;
Nearest TSS
ENST00000473358/Upstream/177410; ENST00000425113/Downstream/164643;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/177478, chr1-CpG: 74/Downstream/164743
Nearby gene
PLPPR5(No orient, 50612)
Upstream sequence
cctgagtagttgggactacaggtgcacaccagcatgcccaactaaactttgaaaaattttgtagacaggaggtctccctatgttgcctatactggtctca
Downstream sequence
aacacctgggctccagcagtcctcctgcctcagcctcccaaagtgctgcgaatacaggcatgagacaccacacctggcAGATTATATAATTTTAAAAGTT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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