Basic Information
VIS ID
TVIS44003303
Fusion event
HTLV-1-MIR5694 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q26.12
Reference genome
GRCh37/hg19
Start
122350760/120591248 (Hg38)
End
122350760/120591248 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA10D ; FRA10F ; FRA10A ; FRA10B
Target gene
MIR5694
Nearest miRNA
hsa-mir-107/Upstream/632656; hsa-mir-202/Downstream/1825717;
Nearest TSS
ENST00000439456/Upstream/16060; ENST00000623529/Downstream/6701;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/133383, chr10-CpG: 32/Downstream/259918
Upstream sequence
AGCCCTGGGCTGCGTGTGCAAGTTAGAAGCATCAGAATATCTTTGATCAGCCATTTCTGTTAAGCTCCATGGGCTTAAGCTTGGAGTGCATGTACCACTG
Downstream sequence
ACTATGCTCCATGAGCCCCAGTGCAGCCCTCTCCAGCCCTGGTCCTTCCAAACTGGCTTTGGCACGGTCATGTGATTGTCCCCTGGATGGAGTGGGAGAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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