Basic Information
VIS ID
TVIS44003316
Fusion event
HTLV-1-RPS19P1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
18485573/18504929 (Hg38)
End
18485573/18504929 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA20A
Target gene
RPS19P1
Nearest miRNA
hsa-mir-103a-2/Upstream/34238; hsa-mir-1-1/Downstream/7703257;
Nearest TSS
ENST00000382410/Upstream/7686; ENST00000474619/Downstream/2553;
Nearest CpG islands
chr20-CpG: 23/Target, None/Upstream, None/Downstream
Nearby gene
SEC23B(+2615) ;
Upstream sequence
CCAGGGTGGCGCTGGGGTTGGCTCCATGACCAAGATCTATGGGGACGTCAGAGAAACGGCGTCATGCCCAGCCACTTCGGCCGAGGCTTCAAGAGTGTCC
Downstream sequence
TCCGCCGGGTCCTCCAAGCCCTGGAGGGGCTGAAAATGGTGGAAAAGGACCAAGATGGGGGCCGCAAACTGACACCTCAGGGACAGAGAGATCTGGGCAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate