Basic Information
VIS ID
TVIS44003324
Fusion event
HTLV-1-PSMG3-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
1612857/1573221 (Hg38)
End
1612857/1573221 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA7B
Target gene
PSMG3-AS1
Nearest miRNA
hsa-mir-339/Upstream/550195; hsa-mir-10399/Downstream/270959;
Nearest TSS
ENST00000635602/Upstream/2216; ENST00000421380/Downstream/47433;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/2820, chr7-CpG: 17/Downstream/28847
Upstream sequence
gtctcaatctcctgacctcaggtgatctgcccgcctcggcctcccaaagtgctgggattacagacgtgagcacccagcctggatgttgtttttgatgaca
Downstream sequence
ctgctaagcacttatgtgagggattgtttgggtggtttgggtctagatctaagataaagacagtaggaaagaaatgagaggtggaaggttgtcctaggct
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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