Basic Information
VIS ID
TVIS44003327
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
21471916/21614405 (Hg38)
End
21471916/21614405 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/3932748; hsa-mir-10400/Downstream/630561;
Nearest TSS
ENST00000518652/Upstream/316166; ENST00000520754/Downstream/173754;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1310231, chr8-CpG: 24/Downstream/136161
Nearby gene
GFRA2(-77614) ;
Upstream sequence
CTTGAAGGACTTCCATAATGTCATGTACTATAGGAATTCCTCCAGGCACAGCACACCCGCAGCCAGGGGACATCCACAAAAATGCTTACCTGTGGTACCA
Downstream sequence
GTAACAAGAACACAAATGGCTTGCCGGGTGCCCACACCGCATGTCTCCTGCCACTTTCTGAAGAATGACACCAAGGCAGCAGATATTACGGCCCCCTTGA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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