Basic Information
VIS ID
TVIS44003332
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.12
Reference genome
GRCh37/hg19
Start
226517598/226329897 (Hg38)
End
226517598/226329897 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1H
Nearest miRNA
hsa-mir-101-1/Upstream/407755; hsa-mir-1182/Downstream/1611693;
Nearest TSS
ENST00000473358/Upstream/20028; ENST00000467495/Downstream/32355;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/20097, chr1-CpG: 82/Downstream/77735
Nearby gene
LIN9(-20149) ;
Nearest cancer related gene
LIN9(TSG, -20149) ;
Upstream sequence
ccacaaatattcatggcagctattattaataaaactattattaataaagctgccatgaatatgcatgtacaagtcttttggggctcatgggatttcattc
Downstream sequence
tcttgggtaaatacctaggaatggaatggttgggtcatatggtgggtacatatttaactttataagaacctgccaaatggatttccaaggtggctgtgcc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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