VISDB Viral Integration Site DataBase

VIS ID

TVIS44003334

Fusion event

HTLV-1-SERPINH1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr11

Cytoband

q13.5

Reference genome

Start

End

75281354/75570309 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-484 ; hsa-mir-29b-3p ; hsa-mir-3591-5p ; hsa-mir-5197-3p ; hsa-mir-664a-5p ; hsa-mir-4517 ; hsa-mir-4794 ; hsa-mir-3064-5p ; hsa-mir-4750-3p ; hsa-mir-5002-5p ; hsa-mir-6504-5p ; hsa-mir-6859-3p ; hsa-mir-7158-5p ; hsa-mir-1827 ; hsa-mir-762 ; hsa-mir-4446-3p ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4721 ; hsa-mir-5001-5p ; hsa-mir-5580-5p ; hsa-mir-29a-3p ; hsa-mir-29c-3p ; hsa-mir-767-5p ; hsa-mir-96-5p ; hsa-mir-1271-5p ; hsa-mir-182-5p ; hsa-mir-7150 ; hsa-mir-1200 ; hsa-mir-378a-5p ; hsa-mir-9-5p ; hsa-mir-3667-3p ; hsa-mir-3140-5p ; hsa-mir-5088-3p ; hsa-mir-361-3p ; hsa-mir-370-5p ; hsa-mir-1304-5p ; hsa-mir-6765-5p ; hsa-mir-6893-5p ; hsa-mir-940 ; hsa-mir-6808-5p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-4726-3p ; hsa-mir-149-5p ; hsa-mir-199b-5p ; hsa-mir-199a-5p ; hsa-mir-1825 ; hsa-mir-4463 ; hsa-mir-892b ; hsa-mir-6741-5p ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-6836-3p ; hsa-mir-6749-3p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-548v ; hsa-mir-187-5p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-1283 ; hsa-mir-5193 ; hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-133b ; hsa-mir-133a-3p ; hsa-mir-142-3p ; hsa-mir-6846-3p ; hsa-mir-6854-5p ; hsa-mir-1193

Nearest miRNA

hsa-mir-10392/Upstream/235123; hsa-let-7a-2/Downstream/3831713;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/3322, chr11-CpG: 74/Downstream/12713

Upstream sequence

TCCTTGGATGCCACAAATGGTTCTCACCTGCAGAATCGATCCAGACTTGCTGCCCAGAGAGCTTGGAGAGATAAAGCTGGAGATGAAGTGGGGCTTAGGC

Downstream sequence

TCCAAACCAGGGACAAGTGGAGCTCGTACTGGTCTGTGCTGTAGACCCTGGGAGTTCCTGGAGAGGGGTCACTGTCTCTCTCCTGGTCCTGGCCCTGATC