Basic Information
VIS ID
TVIS44003339
Fusion event
HTLV-1-MYRFL integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q15
Reference genome
GRCh37/hg19
Start
70284299/69890519 (Hg38)
End
70284299/69890519 (Hg38)
Orient
-
Location type
Intronic
Target gene
MYRFL
Nearest miRNA
hsa-let-7i/Upstream/305696; hsa-mir-1178/Downstream/9528738;
Nearest TSS
ENST00000382841/Upstream/65203; ENST00000299350/Downstream/36056;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/150740, chr12-CpG: 102/Downstream/352318
Upstream sequence
ATGCTTTCATTTGGCAAGAATTGTACTTCTggccgggtgtggtagctcacacctgtaatcctagcactttggggtgctgaggtggttgggatcacttgag
Downstream sequence
gtcaggagtttgaaacccagcctggccaacatggcgaaaccctgtctctactaaaaatacaaaaattagccgggcgtggtggtgtgcacctgtagtccca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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