Basic Information
VIS ID
TVIS44003343
Fusion event
HTLV-1-LOC105369896 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
92001295/91607518 (Hg38)
End
92001295/91607518 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12B
Target gene
LOC105369896
Nearest miRNA
hsa-let-7i/Upstream/4862369; hsa-mir-1178/Downstream/2954271;
Nearest TSS
ENST00000382841/Upstream/245322; ENST00000617041/Downstream/27369;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/653199, chr12-CpG: 128/Downstream/537416
Nearby gene
LINC01619(No orient, 377457)
Upstream sequence
ATTTAGATCCAATATCATCagttccatgacaataggtgctatatccattttgttcaatattgtattttcaatatttagctcattatctaggacatggtag
Downstream sequence
gTATCTGTCACGGTAATAAATGACAAAATTAAAATGCTTGAATTCTGCTACATGGAGTAGAATTGAAAACCTCTACATTTAGAAGGGCCCATCAGATACA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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