VISDB Viral Integration Site DataBase

VIS ID

TVIS44003350

Fusion event

HTLV-1-ATP5F1A integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr18

Cytoband

q21.1

Reference genome

Start

End

43671069/46091103 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1301-3p ; hsa-mir-1229-3p ; hsa-mir-877-3p ; hsa-mir-18a-3p ; hsa-mir-149-5p ; hsa-mir-23b-3p ; hsa-mir-100-5p ; hsa-mir-92a-3p ; hsa-mir-26a-5p ; hsa-mir-23a-3p ; hsa-mir-16-5p ; hsa-mir-6516-5p ; hsa-mir-6781-5p ; hsa-mir-6877-5p ; hsa-mir-31-5p ; hsa-mir-139-3p ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-4649-3p ; hsa-mir-5091 ; hsa-mir-194-3p ; hsa-mir-3123 ; hsa-mir-302f ; hsa-mir-6870-3p ; hsa-mir-216a-5p ; hsa-mir-548c-3p ; hsa-mir-7977 ; hsa-mir-4536-5p ; hsa-mir-383-3p ; hsa-mir-1228-3p ; hsa-mir-4318 ; hsa-mir-371a-5p ; hsa-mir-3613-3p ; hsa-mir-6895-5p ; hsa-mir-1972 ; hsa-mir-6508-3p ; hsa-mir-4726-5p ; hsa-mir-4640-5p ; hsa-mir-6853-5p ; hsa-mir-4755-3p ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-5693 ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-5582-5p ; hsa-mir-372-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-6827-3p ; hsa-mir-340-3p ; hsa-mir-1233-5p ; hsa-mir-125b-2-3p ; hsa-mir-1288-5p ; hsa-mir-1292-3p ; hsa-mir-134-3p ; hsa-mir-1910-3p ; hsa-mir-3689d ; hsa-mir-3714 ; hsa-mir-3974 ; hsa-mir-4457 ; hsa-mir-4459 ; hsa-mir-4514 ; hsa-mir-4537 ; hsa-mir-4648 ; hsa-mir-4654 ; hsa-mir-4692 ; hsa-mir-4769-5p ; hsa-mir-513b-5p ; hsa-mir-5583-3p ; hsa-mir-6134 ; hsa-mir-624-3p ; hsa-mir-6511a-5p ; hsa-mir-6778-5p ; hsa-mir-6840-3p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-7847-3p

Nearest miRNA

hsa-mir-1-2/Upstream/1120937; hsa-mir-122/Downstream/1289393;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/18614, chr18-CpG: 39/Downstream/6887

Upstream sequence

TCTTACAGCTAATGATAACTTTGGGCTCTGTAATTATTCTTCCACATCAAGTGGCTCTTTTTCCGTAGTAGACATTACCAAGAGTATCAAGACTATCTTT

Downstream sequence

TCCCATATCTGCATGCCTACTAGACAGTTCCACTCTCTCTAGTTTATCCAGATGTCATCCTCTGCTTTCCCTAACTCCTACAACTTATTTCTCATACCCT