VISDB Viral Integration Site DataBase

VIS ID

TVIS44003354

Fusion event

HTLV-1-LIMS1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q12.3

Reference genome

Start

End

109236246/108619790 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-421 ; hsa-mir-590-3p ; hsa-mir-340-5p ; hsa-mir-1-3p ; hsa-mir-221-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-1226-3p ; hsa-mir-744-5p ; hsa-mir-18a-3p ; hsa-mir-505-3p ; hsa-mir-513a-3p ; hsa-mir-619-3p ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-4774-5p ; hsa-mir-7851-3p ; hsa-mir-6507-5p ; hsa-mir-129-5p ; hsa-mir-507 ; hsa-mir-557 ; hsa-mir-4279 ; hsa-mir-4777-3p ; hsa-mir-4503 ; hsa-mir-4477a ; hsa-mir-4693-5p ; hsa-mir-4729 ; hsa-mir-6792-5p ; hsa-mir-4318 ; hsa-mir-892a ; hsa-mir-29c-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-3680-3p ; hsa-mir-450b-5p ; hsa-mir-5698 ; hsa-mir-8057 ; hsa-mir-6836-3p ; hsa-mir-5001-3p ; hsa-mir-143-5p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-504-3p ; hsa-mir-3194-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-6499-3p ; hsa-mir-2276-3p ; hsa-mir-1304-3p ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-5693 ; hsa-mir-6890-3p ; hsa-mir-6796-3p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-122-5p ; hsa-mir-3135b ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-6741-3p ; hsa-mir-30d-5p

Nearest miRNA

hsa-mir-1285-2/Upstream/6187424; hsa-mir-10b/Downstream/521700;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/84945, chr2-CpG: 105/Downstream/99522

Upstream sequence

aaaacaaaacaaaacaaaaAGAATTGGATACTTCAGGAGTTCTAAATTGAAATGTTTCTATTACTGTAAACTAAATTGTTTGGTATTTAAATCTTCTACA

Downstream sequence

TTCTATTTGTTTTTGAGTGGCAATATATTCAAAGTTCAGAAGGTGTAGAGTGGTGTGTGTAGTGGAAATGCTTCCTTCTGCTTCTGTCTCCCCAGGTCCC