Basic Information
VIS ID
TVIS44003363
Fusion event
HTLV-1-CHCHD6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
126597019/126878176 (Hg38)
End
126597019/126878176 (Hg38)
Orient
-
Location type
Intronic
Target gene
CHCHD6
miRNAs that regulate target gene
hsa-mir-296-3p
Nearest miRNA
hsa-let-7g/Upstream/1087624; hsa-mir-12124/Downstream/697090;
Nearest TSS
ENST00000440867/Upstream/23312; ENST00000504973/Downstream/56948;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/173410, chr3-CpG: 27/Downstream/71240
Upstream sequence
agctagagttctcactgtaggggacagaaggtgcaaaaatggaatggaggaagaaagagccttgtggtcttggtttggaataagcagaatcaatatgaat
Downstream sequence
tcagggttttaaagaagtctatttttcccagctttgttcccggaaagaacactgaaagtgaagacacatcagtagtagtaagcactcctttcacctaaat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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