Basic Information
VIS ID
TVIS44003369
Fusion event
HTLV-1-NSG1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
4399611/4397884 (Hg38)
End
4399611/4397884 (Hg38)
Orient
-
Location type
Intronic
Target gene
NSG1
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-7977 ; hsa-mir-6515-3p ; hsa-mir-1236-3p ; hsa-mir-6827-3p ; hsa-mir-6764-5p ; hsa-mir-340-3p ; hsa-mir-1915-3p ; hsa-mir-4685-5p ; hsa-mir-6837-5p ; hsa-mir-3918
Nearest miRNA
hsa-mir-4800/Upstream/2147728; hsa-mir-12113/Downstream/1525391;
Nearest TSS
ENST00000502981/Upstream/10779; ENST00000499430/Downstream/25804;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/9692, chr4-CpG: 72/Downstream/143826
Upstream sequence
GCCCAGATCCTGTTTGTATTTCTCTGTTCCCGGCTGTTCTTTCCAGAAAACACTCCTCAGGTCTCCCTTGCCTTCCACTGGGGCTCATGGCCTCTTGTCA
Downstream sequence
GCACACCCACAATAGTTTGCGACACCAGCCTCCCGCCTCTCTCCTCTGGCCCATTCTttatttttttctttttcttttttactttttgagatggagtctt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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