Basic Information
VIS ID
TVIS44003380
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p12
Reference genome
GRCh37/hg19
Start
34909321/35051803 (Hg38)
End
34909321/35051803 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/5094455; hsa-mir-10400/Downstream/6219245;
Nearest TSS
ENST00000518652/Upstream/267751; ENST00000474634/Downstream/183654;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1328721, chr8-CpG: 103/Downstream/183358
Nearby gene
UNC5D(+183654) ;
Nearest cancer related gene
UNC5D(TSG, +183654) ;
Upstream sequence
cttatcctctatgttactcagtttccttgtttgtaaagtatcatacaccatataaaacttaattacctcaaaggttgtagatgaaaaatgtatcaacata
Downstream sequence
aatgaaattctttgaataatacctgatgtacaatcagtgctacatcagtgttatttattactTTGCTACAGATGCCACTATTTTATTAGGTTTTGCCAGA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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